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br Introduction Neurofibromin Merlin NF is
2018-10-23
Introduction Neurofibromin 2 (Merlin, NF2) is a tumour suppressor protein expressed during embryonic development and thereafter (Gronholm et al., 2005). In adults, significant levels of expression are found in Schwann and meningeal cells, nerve and lens (Claudio et al., 1997; Sakuda et al., 1996;
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PD is expressed on activated CD and CD T cells
2018-10-23
PD-1 is expressed on activated CD4+ and CD8+ T cells, as well as on B cells, myeloid cells (monocytes and some dendritic cells) and NK T cells, suggesting multiple roles in immune regulation (Keir et al., 2008). Persistent expression of PD-1 on CD8+ T cells leads to exhaustion, associated with decre
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DNA methylation based subgroups of
2018-10-23
DNA methylation-based subgroups of human cancers have been identified that show clinical utility. Evidence of a CpG Island Methylator Phenotype (CIMP) was first described in colorectal cancer as DNA hypermethylation of a subset of CpG islands in a subset of tumors (reviewed in ). CIMP status is also
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Besides beige adipogenesis increasing the progenitor pool in
2018-10-23
Besides beige adipogenesis, increasing the progenitor pool in adipose tissues through angiogenesis has another advantage. It is known that PDGFRα+ progenitor channel modulator are the source of both beige and white adipocytes (Lee et al., 2012; Lee et al., 2013; Lee et al., 2015). Thus, enhancing PD
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Lipid metabolism was the only host process
2018-10-23
Lipid metabolism was the only host process with a qualitatively different induction early in Mtb infection. Host lipid metabolism is known to be significantly impacted by Mtb infection. Fatty acids are accessed by mycobacteria during host cell infection (Lee et al., 2013), and host 5-Iodotubercidin
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A A and A labels were
2018-10-23
A300, A350 and A400 labels were used to indicate the concrete samples produced and cured by drinking water as the control samples, and 300, 350 and 400 indicate the kg/m3 of cement in one cubic meter of concrete. B300, B350, B400 labels were used for the concrete samples produced with drinking water
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br Immunolabeling Isolated mitochondria and
2018-10-23
Immunolabeling Isolated mitochondria and cardiomyocytes (neonatal and adult) were seeded in glass coverslips (0.17-mm thickness) coated with either poly-d-lysine or poly-l-lysine [0.1% (v/v) in PBS], respectively. After, 24h, samples were preloaded with 200nM mitotracker/ER tracker (as described
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br Experimental design materials and methods The vineyard is
2018-10-23
Experimental design, materials and methods The vineyard is located approximately 15.5km east to the nearest Bureau of Meteorology (BOM) weather station (Ararat Prison Station, Vic, Australian BOM Station No. 089085). The long-term mean January temperature (MJT) and annual average rainfall recorde
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br Experimental design materials and methods br Data
2018-10-23
Experimental design, materials and methods Data The data reported include supporting information to the phylogenetic analyses of Franchi et al. [1]. They consist of transcript sequences, sequence alignments and comparisons of four apoptosis-related genes identified in the recently-obtained tra
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Acknowledgements This research is sponsored
2018-10-23
Acknowledgements This research is sponsored by the Covenant University Centre for Research, Innovation and Discovery (CUCRID). Data In the first set of experiments, sessions lasted about two hours and subjects earned on average 18 Euros (about 24 US Dollars at the time of the experiment), inclu
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bcr-abl inhibitor A software based GillAc basic
2018-10-22
A software-based GillAc basic electrochemical system was used to conduct potentiodynamic polarization tests to study the pitting corrosion behaviors of polished samples of friction surfaced coatings. All experiments were conducted in an electrolyte of 0.5M H2SO4 + 0.5M NaCl. Steady state potential w
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Nitrogen rich compounds A novel approach in the field of
2018-10-22
Nitrogen-rich compounds A novel approach in the field of energetic materials is to replace some conventional explosives with high-nitrogen compounds. These materials possess a higher proportion of nitrogen by mass, as compared to conventional explosives, so that they derive their energy output from
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Gingival overgrowth is also known as gingival hyperplasia or
2018-10-22
Gingival overgrowth is also known as gingival hyperplasia or gingival fibromatosis, it is usually associated with multiple factors including inflammation, drug use, neoplasias, hormonal disturbances, uncontrolled diabetes and blood dyscrasias [3–5]. In rare cases (1 in 750,000 people), the overgrowt
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Among banks Micco Panizza and
2018-10-22
Among banks, Micco, Panizza, and Yanez (2006) investigate whether the performance of public and private banks is driven by political considerations during the 1995 to 2002 period. They find that state-owned banks located in developing countries have lower profitability and higher costs than their pr
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Introduction Interest is an inseparable part
2018-10-22
Introduction Interest is an inseparable part of today׳s economic activities and it NS-398 cost is also the main reason of fluctuation and hurdles in economic development because of interest rate money is considered as commodity rather than medium of exchange and it creates unequal distribution of
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