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Quantitative sensory testing QST is a
2018-11-05
Quantitative sensory testing (QST) is a standardized technique to assess human somatosensory function and document altered nociceptive signal processing (Backonja et al., 2013). By determining pain and detection threshold to external mechanical and thermal stimuli, sensory profiles are generated tha
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compellingly demonstrated that NSG mice develop
2018-11-05
compellingly demonstrated that NSG mice develop a human immune system and leukemia, and further show that RLI mediated anti-leukemia activity in the presence of lymphopenia conditions presenting the translational research community with a tractable model system to study leukocyte infusions for immu
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g protein coupled receptors In this issue of EBioMedicine En
2018-11-05
In this issue of EBioMedicine, Enroth and colleagues () present a comprehensive study that analyzes the individual contribution of factors related to the collection and long-term sample storage in a highly homogenous group of Northern European subjects (). Taking advantage of the sampling strategy o
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The racial disparity in US
2018-11-05
The racial disparity in US rates of cancer (among other diseases) has been well-characterized and continues to persist with African-Americans having generally worse cancer incidence and mortality than Whites (). While many researchers have identified proximal causes for this disparity current resear
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HIV subtype C isolates are less fit than subtype
2018-11-05
HIV-1 subtype C isolates are less fit than subtype A which are both less fit than subtype B and D HIV-1 isolates, a finding established by over 2000 direct head-to-head dual virus competitions in primary CD4+ T-cells and macrophages from HIV-negative donors of different races/ethnicities (Abraha et
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br Materials and Methods br Results br
2018-11-05
Materials and Methods Results Discussion Psoriasis is a chronic systemic inflammatory and an autoimmune skin disease. It is histologically characterized by KC hyperproliferation, inflammation, and increased angiogenesis (Bachelez, 2005; Nestle et al., 2009). Although considerable progress i
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br Numerous studies have reported H the first discovered
2018-11-05
Numerous studies have reported H19, the first discovered long non-coding RNA (lncRNA), to have key regulatory functions in tumor development and progression (). This paternally imprinted gene is located close to the telomeric region of chromosome 11p15.5 that frequently harbors genetic alterations
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Therefore given that vocal pitch is a
2018-11-05
Therefore, given that vocal pitch is a defining characteristic that conveys personality and distinguishes it fluoxetine hydrochloride from others (Piñeiro Otero, 2010; Tigue, Borak, O’Connor, Schandl, & Feinberg, 2012), the question that arises when considering the common practice in radio is the f
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The data for m z and m z were
2018-11-05
The data for m/z 10 and m/z 11 were collected simultaneously on L3 and H3 Faraday cups. Their on-peak-zero was measured for 27 s before the laser was on. After the laser was powered on, the measurements were taken in 400 cycles for each spot, and the integration time for each cycle was of 0.131 s. T
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In order to analyze and illustrate Table Figs steepness of
2018-11-05
In order to analyze and illustrate (Table 1, Figs. 2–3) steepness of changes in the EEG indexes during transitions from one stage to another, one-min values were further averaged on 3-min intervals (i.e., from minute −4 to −2, from −1 to +1, from +2 to +4, etc.). Additionally, all positive and negat
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Since the normal mechanism of
2018-11-05
Since the normal mechanism of functioning of the system has not yet been discovered, any new theoretical framework of a mechanism is expected to provide an explanation for the functional role of sleep [18]. Difficulties in understanding the mechanisms of higher lxr agonists functions still continue,
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Pandi Perumal and Gonfalone presented perspective
2018-11-05
Pandi-Perumal and Gonfalone presented perspective on sleep in space by overviewing the past medical reports . The authors made special emphasis on “normal sleep” in space, where no gravity exists. According to their review, sleep in space was mainly monitored by subjective sleep diaries and actigrap
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Traditional methods for the detection of
2018-11-05
Traditional methods for the detection of ERα include enzyme-linked immunosorbent assay (ELISA) [22], Western blotting [4] and immunohistochemistry [11]. Nevertheless, these methods usually present some shortcomings. For example, immunohistochemistry and Western blotting provide typically semiquantit
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br Tasas de inter s
2018-11-03
Tasas de interés “artificialmente bajas” Este fenómeno es lo que a sospecha de muchos (, Economist; 2016) ha provocado que el mundo viva con una inusual y extravagante liquidez global entre los mercados financieros de manera artificial. Como se aprecia en la gráfica 1, tanto las expectativas de
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El papel de organismos econ micos financieros y de
2018-11-03
El papel de organismos económicos, financieros y de cooperación internacional, en la promoción del uso de tic en los últimos 15 años, ha sido de la mayor relevancia, tanto desde el punto de vista teórico, al apoyar la visión de que un uso mayor de tic tiene incidencia sobre la competitividad y el cr
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