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Alterations in Ca TRP ORAI and RYR channels have
2018-10-30
Alterations in Ca TRP, ORAI1 and RYR channels have been identified in cancer (Monteith et al., 2012; Ho et al., 2013; Love et al., 2012), and overexpression of CACNA1E are correlated with relapse in Wilms\' tumors (Natrajan et al., 2006), while CACNA2D1 plays a role in maintaining the properties of
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HPV adjuvanted vaccine Cervarix GSK Vaccines
2018-10-30
HPV-16/18-adjuvanted vaccine (Cervarix®, GSK Vaccines, Belgium) was first licenced in 2007 and is currently licenced in 134 countries for the prevention of persistent infection, pre-cancerous lesions, and cervical and other genital cancers caused by oncogenic HPV. In March 2013 the Japanese press re
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ADCC mediating antibodies target a wide
2018-10-30
ADCC-mediating opioid receptor antagonist target a wide range of epitopes on the envelope (Env) protein, as well as epitopes on Gag (Grunow et al., 1995), Pol (Isitman et al., 2012), Nef (Yamada et al., 2004) and Vpu (Wren et al., 2013; Tiemessen et al., 2009) proteins, though the significance of AD
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CART models identified the most important predictors of mort
2018-10-30
CART models identified the most important predictors of mortality as duration of therapy or follow-up (importance score=100%), CD4+ T cell counts (score=47%), TTP (score=38%), and age (score=21%). The identified thresholds (which partitioned patients to homogenous groups with similar mortality risk)
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One of the overall purposes of
2018-10-30
One of the overall purposes of this work was to catalogue the cell types with evidence of rubella infection in CRS cases. This study extends the description of the pathology of CRS by IHC beyond the single previous report of RV infected histamine receptors in specimens from a single CRS case almost
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PalMitoyl Tripeptide-1 At the cellular level ED is thought t
2018-10-30
At the cellular level, ED is thought to be caused by neuro-vascular or hormonal dysfunction resulting in impaired vasodilatation of penile PalMitoyl Tripeptide-1 (Salonia et al., 2012; Weyne and Albersen, 2014). When the natural nocturnal erection is lost, the penis tissue enters a chronic hypoxic
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br Author Contributions br Conflicts of Interest br Acknowle
2018-10-30
Author Contributions Conflicts of Interest Acknowledgments Introduction ADAMs (a disintegrin and metalloproteinases) are multifunctional proteins involved in ectodomain shedding of transmembrane proteins and thereby regulate cell adhesion, migration, and cell–cell communication. Ectodoma
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Quizartinib Supplier br There is increasing evidence of the
2018-10-30
There is increasing evidence of the important role of innate immune system in tumor surveillance (). The spontaneous immune response of T Quizartinib Supplier against tumors has a powerful prognostic value and can contribute to tumor control in patients. Indeed, T cell-based immunotherapies have
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br Acknowledgments This research was
2018-10-29
Acknowledgments This research was supported by funds from Louisiana State University Health Sciences Center in Shreveport and the Biomedical Research Foundation of Northwest Louisiana. Specifications table Value of the data Data, experimental design, materials and methods The data prese
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br Acknowledgments This work was financially supported
2018-10-29
Acknowledgments This work was financially supported by Simon Fraser University, Stem Cell Network of Canada, Compute Canada, and Westgrid. Y. Z. was supported in part by NNSFC (National Natural Science Foundation of China), Grant no. 21336009. Data The desmosomal cadherin, Desmoglein 3 (Dsg3)
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br Acknowledgements The authors are grateful to the
2018-10-29
Acknowledgements The authors are grateful to the entire members of the Environmental Health (EH) team of African Insect Science for Food and Health (icipe), Agricultural Sector Development Programme (ASDP) team in Zanzibar, and SERVIR through partnership with Kenya-based Regional Centre for Mappi
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We performed one way sensitivity analyses
2018-10-29
We performed one-way sensitivity analyses of the results to changes in our benchmark model parameters (see tornado diagram in Fig. 1). Our results were most sensitive to the specificity rate for the blood pressure device. Our results were insensitive to parameter values that were very high (treatmen
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Unlike quantitative features of the cortical
2018-10-29
Unlike quantitative features of the cortical sheet, such as thickness, surface area (Giedd and Rapoport, 2010) and curvature/gyrification (Armstrong et al., 1995; Li et al., 2014; Raznahan et al., 2011; White et al., 2010) – which can take decades to attain the levels observed in adulthood–the quali
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Our results suggest that timing of ELS may also
2018-10-29
Our results suggest that timing of ELS may also play a role in its associations to neural outcomes. The fact that early but not concurrent ELS related to rs-FMRI might be because the first years of life are times of rapid 2b3a inhibitors development; even mild psychosocial stressors experienced dur
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br Acknowledgements K P H and E M T
2018-10-29
Acknowledgements K.P.H. and E.M.T.D. are Faculty Research Associates of the Population Research Center at the University of Texas at Austin, which is supported by a grant, 5-R24-HD042849, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development. This research was s
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