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br Materials and methods br Results and discussion br
2021-04-27
Materials and methods Results and discussion Conclusions Clitocypin is another member of the mycocypin family of cysteine protease inhibitors that is unique to GSK2879552 shown to exhibit strong insecticidal activity against Colorado potato beetle larvae. This effect is concentration depen
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In these studies the inflammatory cytokine
2021-04-27
In these studies, the inflammatory cytokine IL-8 was demonstrated as one of the responsible molecules induced by CysLTs via activating CysLT2 receptors. IL-8 is synthesized in and released from mononuclear cells, macrophages, fibroblasts and airway epithelial cells, and it promotes inflammation as a
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salidroside Henderson et al reported that allergen
2021-04-27
Henderson et al. [20] reported that allergen-induced airway remodeling was blocked by the CysLT1 receptor antagonist montelukast. The development of epithelial thickening and mucus accumulation at relatively small salidroside was also suppressed by montelukast. The CysLT2 receptor antagonist BayCys
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Cyclopiazonic acid Third we also found negative correlations
2021-04-27
Third, we also found negative correlations between TREM2 mRNA expression and the methylation rate of 4 CpG sites in the intron 1 of TREM2. Gene methylation rates are generally associated with gene expression. Thus, heavily methylated areas of genes are usually less active at the transcriptional leve
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We and others have previously found that
2021-04-27
We and others have previously found that supplementation of old rats with ALCAR remediates the age-related decay in mitochondrial bioenergetics in liver (Hagen et al., 1998a, Hagen et al., 1998b), heart (Paradies et al., 1994, Paradies et al., 1999), muscle (Pesce et al., 2010) and Benidipine HCl (
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Linifanib The data regarding the association between COMT Va
2021-04-27
The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28]. Better performance on the ROCF immediate and delayed recall test among veterans with PTSD who were Met carriers, compared to Val/Val homozygotes, agrees with findings show
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VHb expression in recombinant E coli expressing P
2021-04-27
VHb expression in recombinant E. coli expressing P4H improved Hyp production, presumably by enhancing oxygen transfer. VHb expression contributed to improving growth and extending the period of exponential growth in both shaker flask culture and bioreactor fermentation. A similar phenomenon was also
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Our results demonstrate that pt PGE in addition to
2021-04-27
Our results demonstrate that 17-pt-PGE2 - in addition to its described effects on EP1 and EP3 receptors - also acts as an EP4 agonist and thereby enhances vascular barrier function. Materials and methods Results Discussion In this study we demonstrate that the purported EP1/EP3 receptor ag
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Enolase as a plasminogen receptor and activator localized on
2021-04-27
Enolase, as a plasminogen receptor and activator localized on the surface of several helminths, can interact with the host fibrinolytic system (Yang et al., 2010, Du et al., 2009, de la Torre-Escudero et al., 2010). The enzyme is also one of excretory/secretory (ES) products in some helminths, such
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Despite a high affinity for progesterone and a relatively
2021-04-27
Despite a high affinity for progesterone and a relatively high affinity for testosterone [7], the binding of progesterone and testosterone to CBG is often disregarded [1], [2], [3]. However, the concentrations of these two hormones varies considerably under both normal physiological and pathophysiol
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PRRSV is a single stranded positive sense enveloped RNA
2021-04-27
PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV Pam2CSK4 is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The 3′ end of the genome en
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DNA bound Ku proteins recruit DNA PKcs and thereby
2021-04-26
DNA-bound Ku proteins recruit DNA-PKcs; and thereby translocate into the duplex by one helical turn, leaving DNA-PKcs near the DNA terminus to assist in tethering the broken ends together [25]. In addition to keeping the DSBs in close proximity, DNA-PKcs may prevent exonucleolytic degradation of the
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Studies on the external dehydrogenases of N crassa have
2021-04-26
Studies on the external dehydrogenases of N. crassa have shown that the NDE1 protein is a Ca2+-dependent external NADPH dehydrogenase, while NDE2 is characterized as a dehydrogenase oxidizing both cytosolic substrates (external NADH and/or NADPH) (Carneiro et al., 2004, Melo et al., 2001). All three
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Some limitations to our study should be
2021-04-26
Some limitations to our study should be noted. First, the sample size of our study was limited. As DDR2 mutations are rare in lung SCC, it is possible that the power of our study was insufficient to detect potential associated factors. Second, a significant proportion of the 271 sequenced patients h
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br Experimental section br Results br
2021-04-26
Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised tachykinin receptor did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a p
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