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As with any open label study it
2019-06-10
As with any open-label study, it is possible that a placebo effect may have contributed to patients analgesia after initiation of the therapy. A randomized placebo-controlled trial would be required to finally prove the high analgesic effect of the loading-dose treatment with Ibandronate in metastat
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For HL most previous studies have shown a correlation
2019-06-06
For HL, most previous studies have shown a correlation between decreasing survival rates for patients with HL with decreasing SES, although several studies found no or a varied association between survival outcomes in patients with HL with decreasing SES. The differences in these findings may be att
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The potential improvement in management of patients can be
2019-06-06
The potential improvement in management of patients can be evidenced by a paper comparing baseline symptom severity over two time frames by Khan et al.[17]. Baseline edmonton symptom assessment system (ESAS) scores reported by patients seen from 2006 to 2009 were found to exhibit significant improve
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To more accurately map the del q and to
2019-06-06
To more accurately map the del(7q) and to search for other submicroscopic aberrations, we performed BAC-based array CGH analysis on BM from the accelerated phase. This confirmed an interstitial deletion in chromosome bands 7q22.1-q35 of maximal size 50.0Mb (Fig. 2D). The minimal region of deletion e
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In conclusion describing a single case observation of a
2019-06-06
In conclusion, describing a single case observation of a PV-patient we have for the first time delivered the “proof of concept” that combination therapy with Rux and “low-dose” IFN is safe, tolerable and highly efficacious in PV, as evidenced by a rapid reduction in the JAK2V617F-allele burden in co
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According to the evaluation of guidelines in syncope study
2019-06-06
According to the evaluation of guidelines in syncope study 2 trial (EGSYS-2) score, syncope during effort was one predictor of cardiac syncope (OR, 17.0; 95% CI, 4.1–72.2) [5]. In our study population, 27 of 119 patients (23%) in the non-arrhythmic T-LOC group suffered cardiac syncope, and there was
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The ability of tumors to
2019-06-06
The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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Si en cada figura novelesca habitan en potencia tantas
2019-06-06
Si en cada figura novelesca habitan en potencia tantas identidades como lectores pueda tener, qué decir de un Rimbaud pictórico —la fórmula es de Cassou (1961b: 9)— que se nos ofrece rapsódicamente, descoyuntado, sin ensamblar. Un modelo para armar cuyo formato remite GDC-0994 Supplier otro de los i
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In the trial by Arrossi and
2019-06-06
In the trial by Arrossi and colleagues in Argentina, saha inhibitor health workers randomly allocated to the intervention group delivered self-collection kits to women at their homes during routine visits, instructed women on how to obtain a cervicovaginal sample for HPV testing, and transported th
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El caso argentino sobre la literatura fant stica puede ser
2019-06-06
El caso argentino sobre la literatura fantástica puede ser interpretado de modo similar al de Mukarovsky, MLN 8237 propósito de la obra de arte como hecho semiológico (estético/social): por un lado, se encuentra el signo poético, que Macedonio y Borges recuperan en la obra literaria mediante sus cue
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Otra cuesti n que debi
2019-06-06
Otra cuestión que debió afrontar la política exterior argentina fue la necesidad de recuperar la inserción del país en Latinoamérica. En el abordaje de esta cuestión, como en la referida urat1 inhibitor las situaciones de dependencia, la política exterior contó con un contexto internacional muy perm
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Si consideramos el estado incipiente
2019-06-06
Si consideramos el estado incipiente de la discusión alrededor de este concepto emergente, veremos que un análisis cualitativo más detallado de los textos constitucionales resulta bastante prometedor. Bolivia En el caso boliviano, buen vivir aparece como parte esencial de la refundación del Esta
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br Agradezco a Rosa Mar
2019-06-06
Agradezco buy SP600125 Rosa María o Mirna Paiz Cárcamo la decisión de escribir sobre su experiencia vital en la insurgencia guatemalteca en los años sesenta y, sobre todo, la decisión de publicar sus escritos. Desde la presentación del libro se entiende que en la primera decisión tuvo un papel imp
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pi3k inhibitors Los dedos son las cuatro mil verdades
2019-06-06
Los dedos son las cuatro mil verdades vistas por los ojos de las moscas. La labor del escritor, entonces, se pone pi3k inhibitors la altura de la labor del detective: encontrar los diez dedos, descubrir el cuerpo flotando en el agua, dar con una cabeza que yace en el fondo de un río y nombrarla por
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ap4 Supplier A previous study from our group demonstrated
2019-06-05
A previous study from our group demonstrated that the truncated form of OPG (1-194) has greater activity than the complete form, given that proteoglycans present in the bone tumor microenvironment may bind to full length OPG, thereby limiting its bioavailability and bioactivity [31]. Therefore the t
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